Anesthetic management of antiphospholipid syndrome patients who underwent cardiac surgery: three cases report

Korean Journal of Anesthesiology 2014³â 66±Ç 2È£ p.164 ~ p.168

Á¶Çö¿í(Cho Hyun-Wook) - Seoul National University Hospital Department of Anesthesiology and Pain Medicine
ÀüÀ±¼®(Jeon Yun-Seok) - Seoul National University Hospital Department of Anesthesiology and Pain Medicine
È«´ö¸¸(Hong Deok-Man) - Seoul National University Hospital Department of Anesthesiology and Pain Medicine
±èÇöÁÖ(Kim Hyun-Joo) - Seoul National University Hospital Department of Anesthesiology and Pain Medicine
¹ÎÁ¤Áø(Min Jeong-Jin) - Seoul National University Hospital Department of Anesthesiology and Pain Medicine

Abstract

Antiphospholipid syndrome (APS) is a rare disease in which patients display prolonged coagulation test results in vitro, but usually develop thrombotic symptoms in vivo. Patients with APS are at increased risk of valvular heart disease or coronary vascular disease, conditions that often necessitate cardiac surgery via bypass. The management of anticoagulation during cardiopulmonary bypass (CPB) is particularly challenging in these patients because of the unique features of APS. Patients with APS are constantly at risk of arterial and venous thrombotic events. Therefore it is very important to maintain proper anticoagulation perioperatively, especially during CPB. In this paper, we present three successful cases of APS patients who underwent cardiac surgery with CPB.

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Antiphospholipid syndrome, Cardiopulmonary bypass, Cardiac surgery
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